Protein : CASP2
Owner Public
URN urn:agi-llid:835
Hugo ID 1503
Connectivity 277
Name CASP2
Description caspase 2
Notes may play a role in proteolysis and programmed cell death [RGD]
RGD ID 69274
MGI ID 97295
Pathway Caspases
Death receptor signaling
TNFR1 signaling
Group Proteases
programmed cell death
apoptosis
apoptotic program
regulation of apoptosis
negative regulation of apoptosis
anti-apoptosis
induction of apoptosis
proteolysis
cellular_component
intracellular
nucleus
protein binding
enzyme binding
hydrolase activity
peptidase activity
cysteine-type peptidase activity
caspase activity
GenBank ID NC_000007
NM_032982
NP_116764
NM_032983
NP_116765
NM_001224
NP_001215
NT_007914
NT_079596
NW_923651
AC_000050
AC_000068
AC073342
AAP22346
AAP22347
AAP22348
AAP22349
AY219042
AAO25653
CH236959
AF314174
AAK00299
AF314175
AAK00300
AK096245
BC002427
AAH02427
BM998653
BT007240
AAP35904
BX537669
CB988674
CR541748
CAG46548
CR591430
U13021
AAA58959
U13022
AAA58960
P42575
Q7KZL6
Q86UJ3
Q9BUP7
Q9BZK9
Q9BZL0
NC_000072
NM_007610
NP_031636
NT_039341
NW_000273
NW_001030802
AC_000028
AC153915
AK042072
BAC31153
AK052396
AK133829
AK142569
AK170649
BAE41936
AK184247
AK191150
AK192895
AK193297
AK197928
AK198936
AK199368
AK205872
AK208643
AK210521
AK210856
AK214788
BC034262
AAH34262
D28492
BAA25876
Y13085
CAA73527
P29594
NC_005103
NM_022522
NP_071967
NW_001084827
NW_047690
AC_000072
AF025671
AAB82567
AF136231
AAD33684
AF136232
AAD33685
U34684
AAC52260
U77933
AAB96379
P55215
Source Curated
LocusLink ID 835
12366
64314
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 600639
Alias ICH1
NEDD2
CASP-2
ICH-1L
ICH-1L/1S
caspase 2
ICH-1 protease
NEDD2 apoptosis regulatory gene
caspase 2, apoptosis-related cysteine protease
caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally down-regulated 2)
ICH-1
Caspase-2
GO ID 0030693
0008234
0019899
0005515
0006916
0008632
0006508
0042981
0008372
0005622
0016787
0008233
0006915
0006917
0043066
0005634
0012501
Swiss-Prot Accession P42575
Q7KZL6
Q86UJ3
Q9BUP7
Q9BZK9
Q9BZL0
P29594
P55215
Unigene ID Hs.368982
Mm.3921
Mm.402738
Rn.1438