Protein : TNFRSF1A


Owner	Public
URN	urn:agi-llid:7132
Hugo ID	11916
Connectivity	912
Name	TNFRSF1A
Description	tumor necrosis factor receptor superfamily, member 1a
Notes	may play a role in TNFalpha mediated inflammatory response to spinal cord injury [RGD]


RGD ID	621237


MGI ID	1314884


Cell Localization	Plasma membrane


Pathway	LT-alpha
	TNF-alpha signaling
	Death receptor signaling
	TNFR1 signaling
	TNF-alpha
	Inhibition of Apoptosis
	NF-kB Signaling
	Apoptosis
	MAPK signaling
	TNFRs -> NF-kB signaling pathway
	TNFRSF1A -> AP-1 signaling pathway
	TNFRSF1A -> ATF2 signaling pathway
	TNFRSF1A -> CREB1 signaling pathway
	TNFRSF1A -> ELK1-SRF signaling pathway
	TNFRSF1A -> ELK4-SRF signaling pathway
	TNFRSF1A -> STAT1 signaling pathway
	TNFRSF1A -> STAT3 signaling pathway
	TNFRSF1A -> STAT5A signaling pathway
	TNFRSF1A -> STAT5B signaling pathway
	TNFRSF1A -> STAT6 signaling pathway
	TNFRSF1A -> TP53 signaling pathway
	Copy of 'Apoptosis'
	Apoptosis2


Group	Receptors
	signal transduction
	cell surface receptor linked signal transduction
	cytokine and chemokine mediated signaling pathway
	positive regulation of I-kappaB kinase-NF-kappaB cascade
	activation of MAPK activity
	apoptosis
	prostaglandin metabolism
	electron transport
	positive regulation of transcription from RNA polymerase II promoter
	inflammatory response
	positive regulation of inflammatory response
	defense response
	response to wounding
	extracellular region
	membrane
	plasma membrane
	integral to membrane
	integral to plasma membrane
	protein binding
	tumor necrosis factor receptor activity
	heme binding
	electron carrier activity
	receptor activity


Source	Curated


OMIM ID	191190
	142680


Alias	FPF
	p55
	p60
	TBP1
	TNF-R
	TNFAR
	TNFR1
	p55-R
	CD120a
	TNFR55
	TNFR60
	TNF-R-I
	TNF-R55
	MGC19588
	tumor necrosis factor receptor 1
	tumor necrosis factor-alpha receptor
	tumor necrosis factor receptor type 1
	tumor necrosis factor binding protein 1
	TNF-R1
	Tnfr-2
	TNFRp55
	tumor necrosis factor receptor superfamily, member 1a
	TNF receptor alpha chain
	MGC105478