ProtModification :


Owner	Public
URN	urn:agi-ProtModification:inout-urn:agi-llid:836:out-urn:agi-llid:6093::negative
Entities	CASP3 ---\| Rock1
References	1
Connectivity	2
Effect	negative


MedLine Reference	12759456:1183
Sentence	Zeiotic blebbing in HEK-P2X7 cells in response to ATPa ATP-induced blebbing is blocked by inhibitors of the ROCK kinase, but not by caspase inhibitors The Rho-effector kinase ROCK-I has been shown to play a necessary role in blebbing induced during apoptosis as a result of caspase-3-mediated cleavage of ROCK-I to its constitutively active form.
Source	Curated