Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:8795:inout-urn:agi-llid:8743:
Entities TNFRSF10B ---- TNFSF10
References 63
MedLine Reference 15828026:4
Sentence Conversely, addition in culture of TRAIL-R2-Fc chimera, which blocked the interaction between endogenous TRAIL and TRAIL-R2 on the surface of cultured megakaryocytic cells, increased the total megakaryocytic cell count.
CellType megakaryocyte
MedLine Reference 10072501:4
Sentence When used in solution, one of the anti-TRAIL-R2 mAbs was capable of blocking leucine zipper-human TRAIL binding to TRAIL-R2-expressing cells and prevented TRAIL-induced death of these cells, whereas two of the anti-TRAIL-R1 mAbs could inhibit leucine zipper-human TRAIL binding to TRAIL-R1:Fc.
Organism Mus musculus
MedLine Reference 10383128:10086
Sentence C , the extracellular domain of MK binds TRAIL.
Journal Cancer Res
Journal Reference v59 i12 p2770
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/59/12/2770
Organism Mus musculus
MedLine Reference 16098198:10202
Journal Eur. J. Biochem
Journal Reference v272 i16 p4163
Journal Link http://content.febsjournal.org/cgi/content/full/272/16/4163
MedLine Reference 12097388:10025
Journal J. Immunol
Journal Reference v169 i2 p847
Journal Link http://www.jimmunol.org/cgi/content/full/169/2/847
MedLine Reference 11994437:10022
Journal J. Immunol
Journal Reference v168 i10 p4881
Journal Link http://www.jimmunol.org/cgi/content/full/168/10/4881
MedLine Reference 11486001:10034
Journal J. Biol. Chem
Journal Reference v276 i41 p37879
Journal Link http://www.jbc.org/cgi/content/full/276/41/37879
MedLine Reference 12517970:10211
Journal J. Immunol
Journal Reference v170 i2 p1027
Journal Link http://www.jimmunol.org/cgi/content/full/170/2/1027
MedLine Reference 10754286:10220
Journal J. Immunol
Journal Reference v164 i8 p3961
Journal Link http://www.jimmunol.org/cgi/content/full/164/8/3961
MedLine Reference 11035092:10035
Journal J. Immunol
Journal Reference v165 i8 p4522
Journal Link http://www.jimmunol.org/cgi/content/full/165/8/4522
MedLine Reference 9325248:10089
Journal J. Biol. Chem
Journal Reference v272 i41 p25417
Journal Link http://www.jbc.org/cgi/content/full/272/41/25417
MedLine Reference 15173176:10152
Journal J. Biol. Chem
Journal Reference v279 i33 p35047
Journal Link http://www.jbc.org/cgi/content/full/279/33/35047
MedLine Reference 9311998:10121
Journal EMBO
Journal Reference v16 i17 p5386
Journal Link http://emboj.oupjournals.org/cgi/content/full/16/17/5386
MedLine Reference 14679212:10088
Journal J. Biol. Chem
Journal Reference v279 i9 p8269
Journal Link http://www.jbc.org/cgi/content/full/279/9/8269
Organism Mus musculus
MedLine Reference 9242611:10076
Journal Science
Journal Reference v277 i5327 p818
Journal Link http://www.sciencemag.org/cgi/content/full/277/5327/818
MedLine Reference 12388624:10158
Journal JPET
Journal Reference v303 i2 p461
Journal Link http://jpet.aspetjournals.org/cgi/content/full/303/2/461
Organism Mus musculus
MedLine Reference 11568010:10207
Journal Blood
Journal Reference v98 i7 p2220
Journal Link http://www.bloodjournal.org/cgi/content/full/98/7/2220
MedLine Reference 11468181:10243
Journal Blood
Journal Reference v98 i3 p795
Journal Link http://www.bloodjournal.org/cgi/content/full/98/3/795
Organism Mus musculus
MedLine Reference 10438925:10018
Journal J. Immunol
Journal Reference v163 i4 p1906
Journal Link http://www.jimmunol.org/cgi/content/full/163/4/1906
Organism Mus musculus
MedLine Reference 11544302:10024
Journal J. Immunol
Journal Reference v167 i6 p3164
Journal Link http://www.jimmunol.org/cgi/content/full/167/6/3164
MedLine Reference 10946322:10198
Journal J. Immunol
Journal Reference v165 i5 p2886
Journal Link http://www.jimmunol.org/cgi/content/full/165/5/2886
MedLine Reference 14500373:10028
Journal Cancer Res
Journal Reference v63 i17 p5390
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/63/17/5390
Organism Mus musculus
MedLine Reference 11245478:10164
Journal Cancer Res
Journal Reference v61 i4 p1645
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/61/4/1645
MedLine Reference 12466268:10254
Journal J. Biol. Chem
Journal Reference v278 i7 p5444
Journal Link http://www.jbc.org/cgi/content/full/278/7/5444
Organism Mus musculus
MedLine Reference 10706092:10023
Journal Cancer Res
Journal Reference v60 i4 p847
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/60/4/847
Organism Mus musculus
MedLine Reference 16199534:10248
Journal J. Biol. Chem
Journal Reference v280 i49 p41047
Journal Link http://www.jbc.org/cgi/content/full/280/49/41047
MedLine Reference 15173183:10103
Journal J. Biol. Chem
Journal Reference v279 i32 p33593
Journal Link http://www.jbc.org/cgi/content/full/279/32/33593
Organism Mus musculus
MedLine Reference 11431320:10138
Journal Cancer Res
Journal Reference v61 i13 p4942
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/61/13/4942
MedLine Reference 10582684:10113
Journal Cancer Res
Journal Reference v59 i22 p5683
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/59/22/5683
MedLine Reference 15688023
Sentence TNFSF10 (TRAIL) interacts with TNFRSF10B (DR5)
Source Curated
MedLine Reference 14742697:0
Sentence Tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL) is a member of the tumour necrosis factor-alpha (TNF-alpha) family of cytokines which is known to induce apoptosis upon binding to its death domain-containing receptors, DR4/TRAIL-R1 and DR5/TRAIL-R2.
Source Curated
MedLine Reference 12907654:1419
Sentence Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation.
Source Curated
MedLine Reference 10383128:1091
Sentence The results revealed that TRAIL can bind MK with similar affinity as DR4 and KILLER/DR5 (Fig, 2 C , Lane s 2 -4 ), supporting the hypothesis that MK is a mouse TRAIL receptor.
Source Curated
MedLine Reference 9242611:1091
Sentence Tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL) is a member of the tumour necrosis factor-alpha (TNF-alpha) family of cytokines which is known to induce apoptosis upon binding to its death domain-containing receptors, DR4/TRAIL-R1 and DR5/TRAIL-R2.
Journal Science
Journal Reference v277 i5327 p818 (1997)
Journal Link http://www.sciencemag.org/cgi/content/full/277/5327/818
Source Curated
MedLine Reference 12750477:1143
Journal PNAS
Journal Reference v100 i11 p6523 (1996)
Journal Link http://www.pnas.org/cgi/content/full/100/11/6523
Source Curated
MedLine Reference 12517970:1135
Journal J. Immunol
Journal Reference v170 i2 p1027 (2003)
Journal Link http://www.jimmunol.org/cgi/content/full/170/2/1027
Source Curated
MedLine Reference 11994437:1023
Journal J. Immunol
Journal Reference v168 i10 p4881 (2002)
Journal Link http://www.jimmunol.org/cgi/content/full/168/10/4881
Source Curated
MedLine Reference 11035092:1035
Journal J. Immunol
Journal Reference v165 i8 p4522 (2000)
Journal Link http://www.jimmunol.org/cgi/content/full/165/8/4522
Source Curated
MedLine Reference 10229846:1007
Journal J. Immunol
Journal Reference v162 i10 p6053 (1999)
Journal Link http://www.jimmunol.org/cgi/content/full/162/10/6053
Source Curated
MedLine Reference 10072501:1019
Journal J. Immunol
Journal Reference v162 i5 p2597 (1999)
Journal Link http://www.jimmunol.org/cgi/content/full/162/5/2597
Source Curated
MedLine Reference 11677236:1305
Journal J. Biol. Chem
Journal Reference v277 i1 p575 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/1/575
Source Curated
MedLine Reference 11980895:1037
Journal J. Biol. Chem
Journal Reference v277 i27 p24631 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/27/24631
Source Curated
MedLine Reference 11486001:1036
Journal J. Biol. Chem
Journal Reference v276 i41 p37879 (2001)
Journal Link http://www.jbc.org/cgi/content/full/276/41/37879
Source Curated
MedLine Reference 10521396:1224
Journal Genes & Dev
Journal Reference v13 i19 p2514 (1999)
Journal Link http://www.genesdev.org/cgi/content/full/13/19/2514
Source Curated
MedLine Reference 12823542:1118
Journal Eur. J. Biochem
Journal Reference v270 i13 p2721.html) (1999)
Journal Link http://www.ejbiochem.org/cgi/content/full/270/13/2721.h
Source Curated
MedLine Reference 11245478:1165
Journal Cancer Res
Journal Reference v61 i4 p1645 (2001)
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/61/4/1645
Source Curated
MedLine Reference 10945619:1249
Journal Cancer Res
Journal Reference v60 i15 p4122 (2000)
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/60/15/4122
Source Curated
MedLine Reference 11568010:1205
Journal Blood
Journal Reference v98 i7 p2220 (2001)
Journal Link http://www.bloodjournal.org/cgi/content/full/98/7/2220
Source Curated
MedLine Reference 15163747:5
Source Curated
MedLine Reference 14648068:7
Source Curated
MedLine Reference 12831538:2
Source Curated
MedLine Reference 15721415:1
Source Curated
MedLine Reference 9311998:1017
Source Curated
MedLine Reference 10688869:1309
Source Curated
MedLine Reference 12907626:1027
Source Curated
MedLine Reference 12208743:1024
Source Curated
MedLine Reference 11406568:1021
Source Curated
MedLine Reference 11289151:1003
Source Curated
MedLine Reference 11156424:1020
Source Curated
MedLine Reference 11103780:1019
Source Curated
MedLine Reference 10866303:1069
Source Curated
MedLine Reference 10706092:1022
Source Curated
MedLine Reference 15110168
Source Curated