Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:8772:inout-urn:agi-llid:8717:
Entities FADD ---- TRADD
References 183
MedLine Reference 12887920:5
Sentence In a second step, TRADD and RIP1 associate with FADD and caspase-8, forming a cytoplasmic complex (complex II).
MedLine Reference 11755217:2
Sentence Alternatively, a carboxy terminal death domain protein interaction motif can recruit TRADD, which then recruits FADD/MORT1, and finally procaspase 8.
MedLine Reference 16611896:4
Sentence A coimmunoprecipitation assay also suggested that HCV core protein does not interfere with the TRADD-Fas-associated death domain protein (FADD)-procaspase-8 interaction.
CellLineName HepG 2
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Journal Genes & Dev
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Journal Link http://www.genesdev.org/cgi/content/full/13/19/2514
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Organism Mus musculus
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Organism Mus musculus
CellLineName RK13
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MedLine Reference 8565075:2
Organism Mus musculus
MedLine Reference 15767367:10604
Journal J. Exp. Med
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Organism Mus musculus
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Journal Blood
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Journal Cancer Res
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Journal Link http://cgd.aacrjournals.org/cgi/content/full/13/1/13
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Organism Mus musculus
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Journal Mol. Cell. Biol
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Organism Mus musculus
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Organism Mus musculus
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Journal Link http://www.jbc.org/cgi/content/full/274/47/33684
MedLine Reference 14718646:10177
Journal Toxicological Sciences
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Organism Mus musculus
MedLine Reference 16009710:10267
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/280/36/31360
Organism Mus musculus
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Journal Mol. Cell. Biol
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Journal Link http://mcb.asm.org/cgi/content/full/24/13/5914
Organism Mus musculus
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Journal Mol. Cell. Biol
Journal Reference v22 i17 p6034
Journal Link http://mcb.asm.org/cgi/content/full/22/17/6034
MedLine Reference 9774651:10294
Organism Rattus norvegicus
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MedLine Reference 9115275:10031
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Journal Mol. Cell. Biol
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Journal Link http://mcb.asm.org/cgi/content/full/20/13/4505
MedLine Reference 10521444:10039
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/274/43/30603
MedLine Reference 16581782:10599
Journal Mol. Cell. Biol
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Journal Link http://mcb.asm.org/cgi/content/full/26/8/3071
Organism Mus musculus
MedLine Reference 16611992:10382
Journal Mol. Cell. Biol
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Journal Link http://mcb.asm.org/cgi/content/full/26/9/3505
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Journal Nutrition
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Journal J. Immunol
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Journal Link http://www.jimmunol.org/cgi/content/full/173/3/2011
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Journal Link http://www.jimmunol.org/cgi/content/full/174/3/1701
MedLine Reference 15879150:10800
Journal J. Immunol
Journal Reference v174 i10 p6467
Journal Link http://www.jimmunol.org/cgi/content/full/174/10/6467
Organism Mus musculus
MedLine Reference 16116191:10521
Journal J. Immunol
Journal Reference v175 i5 p3033
Journal Link http://www.jimmunol.org/cgi/content/full/175/5/3033
Organism Mus musculus
MedLine Reference 11438547:10032
Journal J. Biol. Chem
Journal Reference v276 i34 p31906
Journal Link http://www.jbc.org/cgi/content/full/276/34/31906
Organism Mus musculus
MedLine Reference 15310755:10031
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/279/43/44955
MedLine Reference 14532286:10031
Journal J. Biol. Chem
Journal Reference v278 i51 p51613
Journal Link http://www.jbc.org/cgi/content/full/278/51/51613
Organism Mus musculus
MedLine Reference 12881424:10012
Journal EMBO
Journal Reference v22 i15 p3898
Journal Link http://emboj.oupjournals.org/cgi/content/full/22/15/3898
Organism Mus musculus
MedLine Reference 11479302:10022
Journal J. Biol. Chem
Journal Reference v276 i39 p36530
Journal Link http://www.jbc.org/cgi/content/full/276/39/36530
Organism Mus musculus
MedLine Reference 10952991:10147
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Journal Link http://www.jbc.org/cgi/content/full/275/46/36217
MedLine Reference 12107169:10036
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Journal Link http://www.jbc.org/cgi/content/full/277/37/34343
MedLine Reference 10347191:10017
Journal J. Biol. Chem
Journal Reference v274 i23 p16337
Journal Link http://www.jbc.org/cgi/content/full/274/23/16337
Organism Mus musculus
MedLine Reference 12709429:10226
Journal J. Biol. Chem
Journal Reference v278 i31 p29216
Journal Link http://www.jbc.org/cgi/content/full/278/31/29216
MedLine Reference 9688654:10238
Journal Gastr. Liver Phys
Journal Reference v275 i2 pG269
Journal Link http://ajpgi.physiology.org/cgi/content/full/275/2/G269
Organism Rattus norvegicus
MedLine Reference 15797997:10109
Journal Blood
Journal Reference v106 i2 p408
Journal Link http://www.bloodjournal.org/cgi/content/full/106/2/408
MedLine Reference 10766806:10035
Journal J. Biol. Chem
Journal Reference v275 i16 p11814
Journal Link http://www.jbc.org/cgi/content/full/275/16/11814
Organism Mus musculus
MedLine Reference 10383428:10251
Journal J. Biol. Chem
Journal Reference v274 i27 p19211
Journal Link http://www.jbc.org/cgi/content/full/274/27/19211
Organism Mus musculus
MedLine Reference 10358168:10022
Journal J. Immunol
Journal Reference v162 i12 p7217
Journal Link http://www.jimmunol.org/cgi/content/full/162/12/7217
Organism Mus musculus
MedLine Reference 12721308:10178
Journal J. Biol. Chem
Journal Reference v278 i28 p25534
Journal Link http://www.jbc.org/cgi/content/full/278/28/25534
MedLine Reference 10657934:10021
Journal AJRCMB
Journal Reference v22 i2 p147
Journal Link http://ajrcmb.atsjournals.org/cgi/content/full/22/2/147
MedLine Reference 10454539:10024
Journal Mol. Cell. Biol
Journal Reference v19 i9 p5923
Journal Link http://mcb.asm.org/cgi/content/full/19/9/5923
MedLine Reference 15657078:10031
Journal Cell Sci
Journal Reference v118 i3 p497
Journal Link http://jcs.biologists.org/cgi/content/full/118/3/497
Organism Mus musculus
MedLine Reference 16006552:10163
Journal J. Biol. Chem
Journal Reference v280 i36 p31974
Journal Link http://www.jbc.org/cgi/content/full/280/36/31974
MedLine Reference 15169835:10054
Journal Cell Sci
Journal Reference v117 i13 p2641
Journal Link http://jcs.biologists.org/cgi/content/full/117/13/2641
MedLine Reference 11777919:10195
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/277/10/7996
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Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/272/20/13134
MedLine Reference 15590916:10230
Organism Rattus norvegicus
MedLine Reference 9973400:10259
Journal J. Immunol
Journal Reference v162 i3 p1440
Journal Link http://www.jimmunol.org/cgi/content/full/162/3/1440
Organism Mus musculus
MedLine Reference 8943045:10037
Journal PNAS
Journal Reference v93 i24 p13973
Journal Link http://www.pnas.org/cgi/content/full/93/24/13973
MedLine Reference 10753878:10024
Journal J. Biol. Chem
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Journal J. Exp. Med
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Journal J. Biol. Chem
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MedLine Reference 15173180:10038
Journal J. Biol. Chem
Journal Reference v279 i31 p32780
Journal Link http://www.jbc.org/cgi/content/full/279/31/32780
Organism Mus musculus
MedLine Reference 9054379:10241
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/272/11/6918
MedLine Reference 11854271:10177
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Journal Cell
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MedLine Reference 101000336:11026
Journal Cell
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Journal Link http://www.cell.com/cgi/content/full/86/6/937
MedLine Reference 137100067:11222
Journal Mol. Pharm
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Journal Link http://www.cell.com/cgi/content/full/88/3/355
MedLine Reference 101000036:11079
Journal Cell
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Journal Link http://www.cell.com/cgi/content/full/84/2/299
MedLine Reference 11861282:10135
Journal Blood
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MedLine Reference 9242174:10113
Journal Circulation Res
Journal Reference v81 i2 p137
Journal Link http://circres.ahajournals.org/cgi/content/full/81/2/137
MedLine Reference 9144192:10019
Journal PNAS
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Organism Mus musculus
MedLine Reference 10026132:10105
Journal J. Biol. Chem
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Organism Mus musculus
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Organism Mus musculus
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Organism Mus musculus
MedLine Reference 8910423:10203
Journal J. Biol. Chem
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Journal Link http://www.jbc.org/cgi/content/full/271/45/28097
Organism Mus musculus
MedLine Reference 9744859:10092
Journal Genes & Dev
Journal Reference v12 i18 p2821
Journal Link http://www.genesdev.org/cgi/content/full/12/18/2821
Organism Mus musculus
MedLine Reference 15761471
Sentence TRADD interacts with FADD
Source Curated
MedLine Reference 11112409
Sentence FADD interacts with TRADD
Source Curated
MedLine Reference 12796506
Sentence TRADD interacts with FADD. This interaction was modeled on a demonstrated interaction between TRADD and FADD, both from an unspecified species
Source Curated
MedLine Reference 12907607:1622
Sentence TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
Journal Cancer Res
Journal Reference v63 i15 p4375 (2003)
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/63/15/4375
Source Curated
MedLine Reference 12711593:1262
Sentence TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.
CellType Null Lymphocyte
Journal Cell Phys
Journal Reference v285 i2 pC370 (2003)
Journal Link http://ajpcell.physiology.org/cgi/content/full/285/2/C370
Organism mouse
Source Curated
MedLine Reference 10919673:1248
Sentence Recently, RIP has been reported to be cleaved in TNF-induced apoptosis, promoting the interaction between TRADD and FADD and increasing the sensitivity to death receptor triggering (45) .
Journal Cancer Res
Journal Reference v60 i14 p3947 (2000)
Journal Link http://cancerres.aacrjournals.org/cgi/content/full/60/14/3947
Source Curated
MedLine Reference 10719836:1099
Sentence TRADD in turn interacts via its own DD with two other cytoplasmic DD-containing factors, A?A?A?Fas-associating protein with DDA?A?A? (FADD) and A?A?A?receptor interacting proteinA?A?A? (RIP), which then further connect the receptor with downstream activation pathways [ 8 ].
Organ immunologic
Tissue endothelial
CellType neural
Journal PNAS
Journal Reference v276 i34 p31906 (2001)
Journal Link http://www.jbc.org/cgi/content/full/276/34/31906
Organism C-elegans
Source Curated
CellLineName ec
Journal Cell
Journal Reference v86 i6 p937 (1996)
Journal Link http://www.cell.com/cgi/content/full/86/6/937
Source Curated
Journal Cell
Journal Reference v86 i6 p937 (1996)
Journal Link http://www.cell.com/cgi/content/full/86/6/937
Source Curated
CellType b cell
Journal Cell
Journal Reference v85 i6 p803 (1996)
Journal Link http://www.cell.com/cgi/content/full/85/6/803
Source Curated
CellType b cell
Journal Cell
Journal Reference v85 i6 p803 (1996)
Journal Link http://www.cell.com/cgi/content/full/85/6/803
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
MedLine Reference 11598011:1348
Journal EMBO
Journal Reference v20 i20 p5678 (2001)
Journal Link http://embojournal.npgjournals.com/cgi/content/full/20/20/5678
Source Curated
MedLine Reference 9242174:1112
Journal Circulation Res
Journal Reference v81 i2 p137 (1997)
Journal Link http://circres.ahajournals.org/cgi/content/full/81/2/137
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v84 i2 p299 (1996)
Journal Link http://www.cell.com/cgi/content/full/84/2/299
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
Journal Cell
Journal Reference v88 i3 p355 (1997)
Journal Link http://www.cell.com/cgi/content/full/88/3/355
Source Curated
MedLine Reference 11854271:1023
Journal J. Biol. Chem
Journal Reference v277 i18 p15985 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/18/15985
Organism yeast
Source Curated
MedLine Reference 11821416:1049
Journal J. Biol. Chem
Journal Reference v277 i15 p13122 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/15/13122
Source Curated
MedLine Reference 11777919:1196
Journal J. Biol. Chem
Journal Reference v277 i10 p7996 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/10/7996
Source Curated
MedLine Reference 10952991:1147
Journal J. Biol. Chem
Journal Reference v275 i46 p36217 (2000)
Journal Link http://www.jbc.org/cgi/content/full/275/46/36217
Source Curated
MedLine Reference 10766806:1035
Organ liver
CellType hepatocyte
Journal J. Biol. Chem
Journal Reference v275 i16 p11814 (2000)
Journal Link http://www.jbc.org/cgi/content/full/275/16/11814
Organism mouse
Source Curated
MedLine Reference 10753878:1023
Journal J. Biol. Chem
Journal Reference v275 i15 p10838 (2000)
Journal Link http://www.jbc.org/cgi/content/full/275/15/10838
Organism plant
Source Curated
MedLine Reference 10559258:1033
Journal J. Biol. Chem
Journal Reference v274 i47 p33684 (1999)
Journal Link http://www.jbc.org/cgi/content/full/274/47/33684
Source Curated
MedLine Reference 10521444:1039
CellType fibroblast
Journal J. Biol. Chem
Journal Reference v274 i43 p30603 (1999)
Journal Link http://www.jbc.org/cgi/content/full/274/43/30603
Source Curated
MedLine Reference 10383428:1252
Journal J. Biol. Chem
Journal Reference v274 i27 p19211 (1999)
Journal Link http://www.jbc.org/cgi/content/full/274/27/19211
Organism mouse
Source Curated
MedLine Reference 10026132:1106
Journal J. Biol. Chem
Journal Reference v274 i9 p5267 (1999)
Journal Link http://www.jbc.org/cgi/content/full/274/9/5267
Organism mouse
Source Curated
CellLineName EF
MedLine Reference 9744859:1092
Journal Genes & Dev
Journal Reference v12 i18 p2821 (1998)
Journal Link http://www.genesdev.org/cgi/content/full/12/18/2821
Organism mouse
Source Curated
MedLine Reference 10521396:1041
Journal Genes & Dev
Journal Reference v13 i19 p2514 (1999)
Journal Link http://www.genesdev.org/cgi/content/full/13/19/2514
Source Curated
MedLine Reference 10960363:1197
Journal Gastr. Liver Phys
Journal Reference v279 i3 pG622.html (2000)
Journal Link http://ajpgi.physiology.org/cgi/content/full/279/3/G622.h
Organism guinea
Source Curated
MedLine Reference 9449644:1033
Tissue thyroid
Journal Endocrinology
Journal Reference v139 i2 p703 (1998)
Journal Link http://endo.endojournals.org/cgi/content/full/139/2/703
Organism rat
Source Curated
MedLine Reference 10880445:1232
Journal EMBO
Journal Reference v19 i13 p3325 (2000)
Journal Link http://embojournal.npgjournals.com/cgi/content/full/19/13/3325
Organism drosophila
Source Curated
MedLine Reference 12881424:1012
CellType fibroblast
Journal EMBO
Journal Reference v22 i15 p3898 (2003)
Journal Link http://embojournal.npgjournals.com/cgi/content/full/22/15/3898
Organism mouse
Source Curated
MedLine Reference 9153189:1020
Journal J. Biol. Chem
Journal Reference v272 i21 p13471 (1997)
Journal Link http://www.jbc.org/cgi/content/full/272/21/13471
Organism mouse
Source Curated
MedLine Reference 12077131:1237
CellType fibroblast
Journal J. Biol. Chem
Journal Reference v277 i35 p31381 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/35/31381
Organism rat
Source Curated
MedLine Reference 11934887:1038
Journal J. Biol. Chem
Journal Reference v277 i24 p21730 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/24/21730
Organism mouse