Protein : RPS6KA1


Owner	Public
URN	urn:agi-llid:6195
Hugo ID	10430
Connectivity	169
Name	RPS6KA1
Description	ribosomal protein S6 kinase polypeptide 1
Notes	catalyzes the phosphorylation of ETS transcription factor ER81 and other transcription factors [RGD]


RGD ID	620675


MGI ID	104558


Pathway	Inhibition of Apoptosis
	G-protein Coupled Receptor signaling
	CREB signaling
	ERBB2 -> ETV1 signaling pathway


Group	Kinases
	signal transduction
	ribosome biogenesis
	protein amino acid phosphorylation
	positive regulation of transcription
	spindle
	nucleotide binding
	magnesium ion binding
	ATP binding
	transcription factor binding
	transferase activity
	kinase activity
	protein kinase activity
	protein serine-threonine kinase activity
	protein-tyrosine kinase activity
	ribosomal protein S6 kinase activity


GenBank ID	NC_000001
	NM_002953
	NP_002944
	NM_001006665
	NP_001006666
	NT_004610
	NW_921351
	AC_000044
	AL109743
	CAC36348
	AL627313
	CAI14647
	CAI14648
	CAI14649
	AK092955
	BC014966
	AAH14966
	BC039069
	BF982517
	BM836865
	L07597
	AAC82497
	Q15418
	Q5SVM5
	Q5SVM8
	Q5SVM9
	Q9BQK2
	NC_000070
	NM_009097
	NP_033123
	NT_039267
	NW_000213
	NW_001030750
	AC_000026
	AL837508
	AF084468
	AAD11415
	AK132856
	AK148208
	BAE28414
	AK160571
	AK167790
	BAE39820
	AK179546
	AK187954
	AK210375
	AK213589
	AK214145
	BC049076
	AAH49076
	BC094470
	AAH94470
	BG062954
	BG066743
	BG076428
	BG079900
	M28489
	AAA50300
	P18653
	Q505N6
	NC_005104
	NM_031107
	NP_112369
	NW_001084844
	NW_047724
	AC_000073
	M99169
	AAA02872
	Q63531


Source	Curated


LocusLink ID	6195
	20111
	81771


Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus


OMIM ID	601684


Alias	RSK
	HU-1
	RSK1
	MAPKAPK1A
	S6K-alpha 1
	ribosomal protein S6 kinase, 90kDa, polypeptide 1
	p90-RSK 1
	ribosomal protein S6 kinase alpha 1
	ribosomal protein S6 kinase, 90kD, 1
	ribosomal protein S6 kinase, 90kD, polypeptide 1
	dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)
	p90rsk
	ribosomal protein S6 kinase polypeptide 1
	S6 protein kinase (Rsk-1)


GO ID	0005524
	0000287
	0000166
	0004674
	0016740
	0006468
	0007165
	0016301
	0004672
	0004713
	0007046
	0005819
	0004711
	0008134
	0045941


Swiss-Prot Accession	Q15418
	Q5SVM5
	Q5SVM8
	Q5SVM9
	Q9BQK2
	P18653
	Q505N6
	Q63531


Unigene ID	Hs.149957
	Mm.301827
	Rn.34915