Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:4654:inout-urn:agi-llid:4205:
Entities MEF2A ---- MYOD1
References 36
MedLine Reference 15466486:2
Sentence Here, we show that p38 activity facilitates MyoD and Mef2 binding at a subset of late-activated promoters, and the binding of Mef2D recruits Pol II.
Tissue skeletal
Organism Mus musculus
MedLine Reference 9482738:10239
Sentence We have not examined formally whether Mist1 blocks MyoD-MEF2 interactions.
Journal EMBO
Journal Reference v17 i5 p1412
Journal Link http://emboj.oupjournals.org/cgi/content/full/17/5/1412
Organism Mus musculus
MedLine Reference 11110792:10086
Sentence The interaction between MEF2 and MyoD regulates muscle gene expression in vertebrates ( 2 , 4 ).
Journal J. Biol. Chem
Journal Reference v276 i11 p8278
Journal Link http://www.jbc.org/cgi/content/full/276/11/8278
Organism Mus musculus
MedLine Reference 10082523:10213
Journal Mol. Cell. Biol
Journal Reference v19 i4 p2577
Journal Link http://mcb.asm.org/cgi/content/full/19/4/2577
Organism Mus musculus
MedLine Reference 15024082:10361
Journal Mol. Cell. Biol
Journal Reference v24 i7 p2944
Journal Link http://mcb.asm.org/cgi/content/full/24/7/2944
Organism Mus musculus
MedLine Reference 15082771:10339
Journal Mol. Cell. Biol
Journal Reference v24 i9 p3757
Journal Link http://mcb.asm.org/cgi/content/full/24/9/3757
Organism Mus musculus
MedLine Reference 12709441:10196
Journal J. Biol. Chem
Journal Reference v278 i26 p23515
Journal Link http://www.jbc.org/cgi/content/full/278/26/23515
MedLine Reference 15367695:10333
Journal Mol. Cell. Biol
Journal Reference v24 i19 p8790
Journal Link http://mcb.asm.org/cgi/content/full/24/19/8790
Organism Mus musculus
MedLine Reference 16043483:10187
Journal J. Biol. Chem
Journal Reference v280 i37 p32272
Journal Link http://www.jbc.org/cgi/content/full/280/37/32272
Organism Mus musculus
MedLine Reference 7876201:10203
Journal J. Biol. Chem
Journal Reference v270 i9 p4375
Journal Link http://www.jbc.org/cgi/content/full/270/9/4375
MedLine Reference 7559475:10088
Journal J. Biol. Chem
Journal Reference v270 i40 p23246
Journal Link http://www.jbc.org/cgi/content/full/270/40/23246
Organism Mus musculus
MedLine Reference 15173318:10137
Journal Cell Sci
Journal Reference v117 i14 p3021
Journal Link http://jcs.biologists.org/cgi/content/full/117/14/3021
Organism Mus musculus
MedLine Reference 9418854:10220
Organism Mus musculus
MedLine Reference 11809751:10040
Journal J. Biol. Chem
Journal Reference v277 i14 p12310
Journal Link http://www.jbc.org/cgi/content/full/277/14/12310
Organism Mus musculus
MedLine Reference 10973962:10136
Journal J. Biol. Chem
Journal Reference v275 i47 p36750
Journal Link http://www.jbc.org/cgi/content/full/275/47/36750
Organism Mus musculus
MedLine Reference 15870273:10251
Journal Mol. Cell. Biol
Journal Reference v25 i10 p3997
Journal Link http://mcb.asm.org/cgi/content/full/25/10/3997
Organism Mus musculus
MedLine Reference 8925567:10079
Journal Circulation Res
Journal Reference v79 i1 p4
Journal Link http://circres.ahajournals.org/cgi/content/full/79/1/4
Organism Mus musculus
MedLine Reference 14506227:10033
Journal J. Biol. Chem
Journal Reference v278 i49 p49652
Journal Link http://www.jbc.org/cgi/content/full/278/49/49652
Organism Rattus norvegicus
MedLine Reference 12947115:10041
Journal J. Biol. Chem
Journal Reference v278 i45 p44178
Journal Link http://www.jbc.org/cgi/content/full/278/45/44178
Organism Mus musculus
MedLine Reference 8662987:10017
Journal J. Biol. Chem
Journal Reference v271 i24 p14371
Journal Link http://www.jbc.org/cgi/content/full/271/24/14371
Organism Mus musculus
MedLine Reference 11406578:10207
Journal EMBO
Journal Reference v20 i12 p3018
Journal Link http://emboj.oupjournals.org/cgi/content/full/20/12/3018
MedLine Reference 11877423:1138
Sentence MEF2/MyoD complexes can activate the c-Jun promoter.
Source Curated
MedLine Reference 9482738:1229
Sentence We have not examined formally whether Mist1 blocks MyoD- MEF2 interactions.
Source Curated
MedLine Reference 8925567:1079
Sentence There is a close link between the MyoD and MEF-2 families, since the expression of both MyoD and myogenin leads to the induction of MEF-2 activity. 36 MEF-2A and MyoD physically interact through the MADS domain of MEF-2A and three amino acids within the bHLH motif of MyoD and together can activate skeletal muscle gene expression. 37 As well, the myogenin promoter contains a binding site for MEF-2, which in turn can be induced by myogenin. 38 The interplay between the myogenic regulators of the MyoD family and MEF-2 suggests the existence of a complex regulatory circuit to amplify expression of these genes, which is necessary to stabilize the myogenic program (see Fig 1 ).
Journal Circulation Res
Journal Reference v79 i1 p4 (1996)
Journal Link http://circres.ahajournals.org/cgi/content/full/79/1/4
Source Curated
MedLine Reference 14506227:1033
Sentence There is a close link between the MyoD and MEF-2 families, since the expression of both MyoD and myogenin leads to the induction of MEF-2 activity. 36 MEF-2A and MyoD physically interact through the MADS domain of MEF-2A and three amino acids within the bHLH motif of MyoD and together can activate skeletal muscle gene expression. 37 As well, the myogenin promoter contains a binding site for MEF-2, which in turn can be induced by myogenin. 38 The interplay between the myogenic regulators of the MyoD family and MEF-2 suggests the existence of a complex regulatory circuit to amplify expression of these genes, which is necessary to stabilize the myogenic program (see Fig 1 ).
Journal J. Biol. Chem
Journal Reference v278 i49 p49652 (2003)
Journal Link http://www.jbc.org/cgi/content/full/278/49/49652
Source Curated
MedLine Reference 9418854
Source Curated
MedLine Reference 8548800
Source Curated
MedLine Reference 9819381:1357
Source Curated
MedLine Reference 9418911:1053
Source Curated
MedLine Reference 8662987:1144
Source Curated
MedLine Reference 7559475:1084
Source Curated
MedLine Reference 7876201:1203
Journal J. Biol. Chem
Journal Reference v270 i9 p4375 (1995)
Journal Link http://www.jbc.org/cgi/content/full/270/9/4375
Source Curated
MedLine Reference 12709441:1192
Journal J. Biol. Chem
Journal Reference v278 i26 p23515 (2003)
Journal Link http://www.jbc.org/cgi/content/full/278/26/23515
Source Curated
MedLine Reference 11809751:1040
Journal J. Biol. Chem
Journal Reference v277 i14 p12310 (2002)
Journal Link http://www.jbc.org/cgi/content/full/277/14/12310
Source Curated
MedLine Reference 11110792:1084
Journal J. Biol. Chem
Journal Reference v276 i11 p8278 (2001)
Journal Link http://www.jbc.org/cgi/content/full/276/11/8278
Source Curated
MedLine Reference 10973962:1136
Journal J. Biol. Chem
Journal Reference v275 i47 p36750 (2000)
Journal Link http://www.jbc.org/cgi/content/full/275/47/36750
Source Curated