Protein : LMNB2
Owner Public
URN urn:agi-llid:84823
Hugo ID 6638
Connectivity 32
Name LMNB2
Description similar to Lmnb2 protein (predicted)
Notes The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
RGD ID 1563803
MGI ID 96796
Cell Localization Nucleus
Pathway FAS signaling
Caspases
TNFR1 signaling
Group biological_process
nucleus
nuclear lamina
lamin filament
intermediate filament
viral nucleocapsid
molecular_function
structural molecule activity
GenBank ID NC_000019
NM_032737
NP_116126
NT_011255
NW_927173
AC_000062
AC005624
AAC34573
AC011522
M94363
AAB00873
AL560944
BC006513
BC006551
AAH06551
BC009267
BE791439
BE791473
BM757169
BT007441
AAP36109
CR594022
CR596055
CR599500
CR621930
M94362
AAA80979
Q03252
NC_000076
NM_010722
NP_034852
NT_039500
NT_096129
XM_622972
XP_622972
NW_001030416
AC_000032
AC091518
AC152413
AK012232
AK132671
BAE21293
AK180471
AK199324
BC042430
AAH42430
BC051985
AAH51985
BY292126
D13455
BAA02708
X54098
CAA38032
P21619
NC_005106
XM_216850
XP_216850
NW_001084852
XM_001076027
XP_001076027
NW_047773
AC_000075
Source Curated
LocusLink ID 84823
16907
299625
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 150341
608709
Alias LMN2
LAMB2
MGC2721
lamin B2
similar to Lmnb2 protein (predicted)
GO ID 0005554
0005198
0000004
0005882
0005652
0005634
0019013
0005638
Swiss-Prot Accession Q03252
P21619
Unigene ID Hs.538286
Mm.7362