Protein : CASP1

Owner Public
URN urn:agi-llid:834
Hugo ID 1499
Connectivity 432
Name CASP1
Description caspase 1
Notes apoptotic protease that may play a role in inflammation and apoptosis in male sex organs [RGD]

RGD ID 2274

MGI ID 96544

Pathway Caspases

Group Proteases
signal transduction
positive regulation of I-kappaB kinase-NF-kappaB cascade
cell death
apoptosis
regulation of apoptosis
induction of apoptosis
proteolysis
protein processing
response to hypoxia
extracellular region
intracellular
cytoplasm
signal transducer activity
protein binding
hydrolase activity
peptidase activity
cysteine-type peptidase activity
caspase activity
caspase activator activity

GenBank ID NC_000011
NM_001223
NP_001214
NM_033292
NP_150634
NM_033295
NP_150637
NM_033294
NP_150636
NM_033293
NP_150635
NT_033899
NW_925173
AC_000054
AP001153
AA761907
AB102878
BAD89407
AK223503
BAD97223
AY660536
AAT72297
BC041689
AAH41689
BC062327
AAH62327
CR592117
M87507
AAA66942
U13697
AAC50107
U13698
AAC50108
U13699
AAC50109
U13700
AAC50110
X65019
CAA46153
P29466
Q53EY6
Q5FBZ0
Q6DMQ1
Q6GSS3
Q6PI75
NC_000075
NM_009807
NP_033937
NT_039471
NW_000350
NW_001030736
AC_000025
AC141637
U04269
AAA56992
AK132826
AK163069
BC008152
AAH08152
L03799
AAA39306
L28095
AAA20209
P29452
NC_005107
NM_012762
NP_036894
NW_001084863
NW_047797
AC_000076
BC088098
D85899
BAB67770
S79676
AAB35431
U14647
AAA85812
U34621
AAC52259
P43527

Source Curated

LocusLink ID 834
12362
25166

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 147678

Alias ICE
P45
IL1BC
caspase 1
IL1B-convertase
CASP1 nirs variant 1
interleukin 1-beta convertase
interleukin 1-B converting enzyme
caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
IL-1B converting enzyme
interleukin 1 beta-converting enzyme
interleukin 1 beta convertase
interleukin 1, beta, convertase
Interleukin 1beta converting enzyme
caspase 1 apoptosis-related cysteine protease (interleukin 1 beta convertase)

GO ID 0008656
0030693
0008234
0005515
0004871
0043123
0006508
0042981
0007165
0005622
0016787
0008233
0008219
0006917
0016485
0001666
0005737
0005576
0006915

Swiss-Prot Accession P29466
Q53EY6
Q5FBZ0
Q6DMQ1
Q6GSS3
Q6PI75
P29452
P43527

Unigene ID Hs.2490
Mm.1051
Rn.37508