Protein : DFFA
Owner Public
URN urn:agi-llid:1676
Hugo ID 2772
Connectivity 145
Name DFFA
Description DNA fragmentation factor, alpha subunit
Notes inhibitor of DFF40/CAD and caspase-dependent apoptotic DNA fragmentation [RGD]
RGD ID 620334
MGI ID 1196227
Cell Localization Nucleus
Pathway FAS signaling
Caspases
Death receptor signaling
TNFR1 signaling
DR3 and DR4-5 pathways
Group intracellular signaling cascade
apoptosis
DNA fragmentation during apoptosis
induction of apoptosis
intracellular
cytosol
nucleus
protein binding
caspase-activated deoxyribonuclease activity
GenBank ID NC_000001
NM_213566
NP_998731
NM_004401
NP_004392
NT_021937
NW_923572
AC_000044
AL354956
CAI19196
CAI19197
AF087573
AAD32953
AF103799
AAF02419
AK222546
BAD96266
AU121791
BC000037
AAH00037
BC007112
AAH07112
BC007721
AAH07721
BE207821
BT006980
AAP35626
BU956486
CR596851
CR603712
U91985
AAC51249
O00273
Q53HN4
Q5T6G5
Q5T6G6
NC_000070
NM_001025296
NP_001020467
NM_010044
NP_034174
NT_039268
NW_000222
NW_001030773
AC_000026
AL611967
AB009375
BAA24140
AB009376
BAA24141
AK039227
BAC30285
AK051011
BAC34496
AK079634
BAC37710
AK154488
BB183843
BB446076
BC058213
AAH58213
BI736905
BU695917
BY244454
BY636093
O54786
NC_005104
NM_053679
NP_446131
NW_001084844
NW_047727
AC_000073
AF136601
AAF61425
BC100067
AAI00068
Source Curated
LocusLink ID 1676
13347
114214
Organism Homo sapiens
Mus musculus
Rattus norvegicus
OMIM ID 601882
Alias DFF1
ICAD
DFF-45
DNA fragmentation factor, 45kDa, alpha polypeptide
DFF45
DNA fragmentation factor, 45 kD, alpha subunit
DNA fragmentation factor, 45 kD, alpha polypeptide
DFF35
ICAD-L
ICAD-S
A330085O09Rik
DNA fragmentation factor, alpha subunit
GO ID 0004537
0005515
0006309
0006915
0007242
0005829
0005622
0005634
0006917
Swiss-Prot Accession O00273
Q53HN4
Q5T6G5
Q5T6G6
O54786
Unigene ID Hs.484782
Mm.41433
Rn.6514