Protein : PARP1


Owner	Public
URN	urn:agi-llid:142
Hugo ID	270
Connectivity	1359
Name	PARP1
Description	poly (ADP-ribose) polymerase family, member 1
Notes	catalyzes poly (ADP-ribose) protein modification; plays a role in DNA repair and genome stability [RGD]


RGD ID	2053


MGI ID	1340806


Cell Localization	Nucleus


Group	Adp-ribosyltransferase
	telomere maintenance
	protein amino acid ADP-ribosylation
	DNA metabolism
	DNA repair
	base-excision repair
	transcription from RNA polymerase II promoter
	regulation of growth rate
	response to DNA damage stimulus
	intracellular
	nucleus
	protein binding
	NAD binding
	metal ion binding
	zinc ion binding
	DNA binding
	identical protein binding
	transferase activity
	transferase activity, transferring glycosyl groups
	transferase activity, transferring pentosyl groups
	NAD+ ADP-ribosyltransferase activity


Source	Curated


OMIM ID	173870


Alias	PARP
	PPOL
	ADPRT
	ADPRT1
	PARP-1
	pADPRT-1
	RP11-125A15.2
	poly (ADP-ribose) polymerase family, member 1
	poly(ADP-ribose) polymerase
	poly(ADP-ribose) synthetase
	poly(ADP-ribosyl)transferase
	ADP-ribosyltransferase NAD(+)
	ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
	Adprp
	C80510
	sPARP-1
	AI893648
	5830444G22Rik
	ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
	ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1
	MGC93658
	ADP-ribosyltransferase 1
	poly(ADP-ribose) polymerase PARP-1