Protein : CASP7


Owner	Public
URN	urn:agi-llid:840
Hugo ID	1508
Connectivity	331
Name	CASP7
Description	caspase 7
Notes	member of the cysteine-aspartic acid protease (caspase) family that mediates terminal phase of apoptosis [RGD]


RGD ID	620944


MGI ID	109383


Pathway	FAS signaling
	Caspases
	Death receptor signaling
	Inhibition of Apoptosis
	DR3 and DR4-5 pathways
	Apoptosis
	Copy of 'Apoptosis'
	Apoptosis2


Group	Proteases
	apoptosis
	apoptotic program
	regulation of apoptosis
	release of cytochrome c from mitochondria
	induction of apoptosis
	proteolysis
	heart development
	response to UV
	cytoplasm
	endoplasmic reticulum membrane
	mitochondrial membrane
	protein binding
	hydrolase activity
	peptidase activity
	cysteine-type peptidase activity
	caspase activity


GenBank ID	NC_000010
	NM_033340
	NP_203126
	NM_033338
	NP_203124
	NM_033339
	NP_203125
	NM_001227
	NP_001218
	NT_030059
	NW_924884
	AC_000053
	AL592546
	CAI12638
	CAI12639
	CAI12640
	AL627395
	CAI16004
	CAI16005
	CAI16006
	AK223489
	AU130224
	BC015799
	AAH15799
	BP429646
	BQ007179
	BT006683
	AAP35329
	BX487250
	BX647973
	CR591113
	U37448
	AAC50303
	U37449
	AAC50304
	U39613
	AAC50346
	U40281
	AAC50352
	U67206
	AAF21460
	U67320
	AAC51153
	P55210
	Q53YD5
	Q5SVL0
	Q5SVL2
	Q5SVL3
	NC_000085
	NM_007611
	NP_031637
	NT_039687
	NW_000148
	NW_001030648
	AC_000041
	AC115771
	AC166746
	AK079250
	AK081718
	BAC38305
	AK154978
	BC005428
	AAH05428
	CT010348
	CAJ18556
	D86353
	BAA19730
	U67321
	AAC53068
	Y13088
	CAA73530
	P97864
	NC_005100
	NM_022260
	NP_071596
	NW_001084775
	NW_047569
	AC_000069
	AF072124
	AAC24011
	BC070936
	AAH70936
	O88550


Source	Curated


LocusLink ID	840
	12369
	64026


Organism	Homo sapiens
	Mus musculus
	Rattus norvegicus


OMIM ID	601761


Alias	MCH3
	CMH-1
	ICE-LAP3
	caspase 7
	Lice2 alpha/beta/gamma
	apoptotic protease MCH-3
	ICE-like apoptotic protease 3
	caspase 7, apoptosis-related cysteine protease
	mCASP-7
	AI314680
	ICE-IAP3
	caspase-7


GO ID	0030693
	0008234
	0008233
	0005515
	0008632
	0006508
	0005737
	0005789
	0031966
	0016787
	0006915
	0007507
	0006917
	0042981
	0001836
	0009411


Swiss-Prot Accession	P55210
	Q53YD5
	Q5SVL0
	Q5SVL2
	Q5SVL3
	P97864
	O88550


Unigene ID	Hs.9216
	Mm.35687
	Rn.53995