Protein : SREBF1


Owner	Public
URN	urn:agi-llid:6720
Hugo ID	11289
Connectivity	778
Name	SREBF1
Description	sterol regulatory element binding factor 1
Notes	transcription factor; binds to the sterol regulatory element 1; regulates the transcription of genes important for sterol biosynthesis [RGD]


RGD ID	69423


MGI ID	107606


Cell Localization	Nucleus


Pathway	Caspases
	IGF1R -> SREBF1 signaling pathway
	INSR -> SREBF1 signaling pathway
	ITGB1 -> SREBF1 signaling pathway


Group	Transcription factors
	cholesterol metabolism
	lipid biosynthesis
	steroid metabolism
	transcription
	regulation of transcription
	regulation of transcription, DNA-dependent
	regulation of transcription from RNA polymerase II promoter
	lipid metabolism
	membrane
	endoplasmic reticulum
	endoplasmic reticulum membrane
	Golgi stack
	nucleus
	nuclear envelope
	integral to membrane
	transcription regulator activity
	DNA binding
	transcription factor activity
	RNA polymerase II transcription factor activity


Source	Curated


OMIM ID	184756


Alias	SREBP1
	sterol regulatory element binding transcription factor 1
	sterol regulatory element binding protein-1
	ADD-1
	SREBP-1
	SREBP-1a
	SREBP-1c
	D630008H06
	RP23-456O18.1
	sterol regulatory element binding factor 1