ProtModification :


Owner	Public
URN	urn:agi-ProtModification:inout-urn:agi-llid:834:out-urn:agi-llid:836::positive
Entities	CASP1 --+> CASP3
References	1
Connectivity	2
Effect	positive


MedLine Reference	9545302:1031
Sentence	Typically, caspase-1 (ICE) activates caspase-3 (CPP32/apopain/YAMA), which then cleaves death substrates such as PARP and lamins ( 37 ).
Source	Curated