ProtModification :


Owner	Public
URN	urn:agi-ProtModification:inout-urn:agi-llid:837:out-urn:agi-llid:834::positive
Entities	CASP4 --+> CASP1
References	1
Connectivity	2
Effect	positive


MedLine Reference	12198138:1196
Sentence	Because caspase-11 is a dual activator of caspase-1 and -3 under pathological conditions, including endotoxic shock, multiple sclerosis, and brain ischemia ( 19 , 31 ), it is critical to identify the mechanisms that regulate its transcriptional activation.
Source	Curated