Protein : APAF1


Owner	Public
URN	urn:agi-llid:317
Hugo ID	576
Connectivity	285
Name	APAF1
Description	apoptotic peptidase activating factor 1
Notes	protein involved in the initiation of apoptosis [RGD]


RGD ID	620575


MGI ID	1306796


Pathway	Caspases
	Mitochondrial control of Apoptosis
	Death receptor signaling
	Inhibition of Apoptosis
	DR3 and DR4-5 pathways
	p53 Signaling
	Apoptosis
	Copy of 'Apoptosis'
	Apoptosis2


Group	development
	apoptosis
	regulation of apoptosis
	caspase activation
	caspase activation via cytochrome c
	induction of apoptosis
	forebrain development
	neural tube closure
	brain development
	nervous system development
	physiological defense response
	defense response
	intracellular
	soluble fraction
	cytosol
	nucleus
	nucleotide binding
	protein binding
	ATP binding
	identical protein binding
	caspase activator activity
	apoptotic protease activator activity


Source	Curated


OMIM ID	602233


Alias	CED4
	apoptotic protease activating factor
	apoptotic protease activating factor 1
	fog
	Apaf-1
	Apaf1l
	KIAA0413
	mKIAA0413
	6230400I06Rik
	forebrain overgrowth
	apoptotic peptidase activating factor 1