ProtModification :


Mechanism	phosphorylation
Owner	Public
URN	urn:agi-ProtModification:inout-urn:agi-llid:5170:out-urn:agi-llid:207::positive
Entities	PDPK1 --+> AKT1
References	461
Connectivity	2
Effect	positive


MedLine Reference	14993219:1062
Sentence	Akt is also phosphorylated and activated by PDK1.
Source	Curated


MedLine Reference	11731414:1019
Sentence	Akt is then further activated by the membrane-associated kinase PDK1, which phosphorylates Akt at Thr 308 (3) .
Journal	Cancer Res
Journal Reference	v61 i23 p8390 (2001)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/61/23/8390
Tissue	bone
Source	Curated


MedLine Reference	11016662:1200
Sentence	PDK1 was known to phosphorylate Akt at Thr 308 residue and Ser 473 residue [in the presence of the fragment of PRK2 (9) ].
Journal	Cancer Res
Journal Reference	v60 i18 p5303 (2000)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/60/18/5303
CellLineName	A 549
Source	Curated


MedLine Reference	14960575:1034
Sentence	Akt-1 is activated by phosphorylation by the kinase PDK-1, following binding through its pleckstrin homology domain to the PI3K lipid products on the plasma membrane.
Source	Curated


MedLine Reference	15684326:1193
Sentence	PI3-kinase??dependent kinase-1 (PDK-1) is an effector of Gab2 and participates in the activation of the protein kinase Akt/PKB, another component of Fc RI signaling ( 33 ).
Source	Curated


MedLine Reference	11804874:1037
Sentence	Once Akt translocates to the cell membrane, a separate kinase, PDK1, phosphorylates Akt on threonine residue 308 and serine residue 473, inducing the kinase activity of Akt ( 17 ).
Journal	AJRCMB
Journal Reference	v26 i2 p224 (2002)
Journal Link	http://ajrcmb.atsjournals.org/cgi/content/full/26/2/224
Source	Curated
CellType	monocyte


MedLine Reference	12702569:1036
Sentence	PIP3 recruits to the plasma membrane through interactions with a pleckstrin homology domain, the serine/threonine kinase Akt, which is then phosphorylated by phosphoinositide-dependent kinase-1 (24) .
Journal	Cancer Res
Journal Reference	v63 i8 p1822 (2003)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/63/8/1822
Source	Curated


MedLine Reference	11549751:1176
Sentence	Phospholipid phosphatase PTEN PIP3, the lipid that is generated by PI3-K, has been shown to activate phosphatidylinositol-dependent kinase (PDK-1), which in turn activates Akt ( Le Good et al . 1998 ).
Source	Curated


MedLine Reference	11980660:1233
Sentence	Whereas both p70S6 kinase and Akt can be phosphorylated by PDK1, p70S6 kinase can also be phosphorylated by PKC by direct binding (37) , although Akt can be dephosphorylated by the same PKC isoform by direct binding as well (35) .
Journal	Cancer Res
Journal Reference	v62 i9 p2630 (2002)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/62/9/2630
Organism	mouse
Source	Curated


MedLine Reference	12444011:1303
Sentence	Evidence suggesting that Akt(Ser473) is autophosphorylated by an intrinsic Akt kinase activity that is stimulated by PDK-1-dependent Akt(Ser308) phosphorylation was derived from studies in which kinase-inactive Akt1(K179M) was expressed in human embryonic kidney cells, (HEK-293E cells), Hep G2 cells ( 47 ), and Chinese hamster ovary cells ( 51 ).
Source	Curated


MedLine Reference	12110540:1207
Journal	Endocrin. Metabol
Journal Reference	v283 i2 pE338 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/283/2/E338
CellLineName	L6
Organism	Mus musculus
Source	Curated
CellType	myoblast


MedLine Reference	11832361:1234
Journal	Endocrin. Metabol
Journal Reference	v282 i3 pE585 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/282/3/E585
Source	Curated


MedLine Reference	11832350:1042
Journal	Endocrin. Metabol
Journal Reference	v282 i3 pE497 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/282/3/E497
CellLineName	3T3 L1
Organism	Mus musculus
Source	Curated
CellType	adipocyte


MedLine Reference	11001751:1141
Journal	Endocrin. Metabol
Journal Reference	v279 i4 pE715 (2000)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/279/4/E715
Organism	Rattus norvegicus
Source	Curated


MedLine Reference	10893325:1196
Journal	Endocrin. Metabol
Journal Reference	v279 i1 pE74 (2000)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/279/1/E74
Source	Curated


MedLine Reference	15116068:1024
Journal	EMBO
Journal Reference	v23 i10 p2071 (2004)
Journal Link	http://embojournal.npgjournals.com/cgi/content/full/23/10/2071
Organism	Mus musculus
Source	Curated


MedLine Reference	14500370:1118
Journal	Cancer Res
Journal Reference	v63 i17 p5370 (2003)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/63/17/5370
Organism	Mus musculus
Tissue	epithelia
Source	Curated


MedLine Reference	10942391:1104
Journal	Blood
Journal Reference	v96 i4 p1449 (2000)
Journal Link	http://www.bloodjournal.org/cgi/content/full/96/4/1449
CellLineName	A20
Source	Curated


MedLine Reference	15087394:1260
Journal	Cancer Res
Journal Reference	v64 i8 p2782 (2004)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/64/8/2782
CellLineName	H157
Source	Curated


MedLine Reference	14500673:1210
Journal	J. Immunol
Journal Reference	v171 i7 p3734 (2003)
Journal Link	http://www.jimmunol.org/cgi/content/full/171/7/3734
CellLineName	MBP+
Source	Curated
CellType	neutrophil


MedLine Reference	15201286:1104
Journal	J. Biol. Chem
Journal Reference	v279 i36 p37997 (2004)
Journal Link	http://www.jbc.org/cgi/content/full/279/36/37997
Organism	Mus musculus
Tissue	retina
Organ	liver
Source	Curated


MedLine Reference	14973075:1166
Journal	Cancer Res
Journal Reference	v64 i4 p1444 (2004)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/64/4/1444
CellLineName	PC-3
Source	Curated


MedLine Reference	14695210:1249
Journal	Cancer Res
Journal Reference	v63 i24 p8930 (2003)
Journal Link	http://cancerres.aacrjournals.org/cgi/content/full/63/24/8930
Organism	Mus musculus
Source	Curated


MedLine Reference	12006370:1132
Journal	Endocrin. Metabol
Journal Reference	v282 i6 pE1385 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/282/6/E1385
CellLineName	3T3 L1
Organism	Mus musculus
Source	Curated
CellType	adipocyte


MedLine Reference	15242977:1094
Journal	Circulation Res
Journal Reference	v95 i4 p372 (2004)
Journal Link	http://circres.ahajournals.org/cgi/content/full/95/4/372
Organism	Rattus norvegicus
Source	Curated


MedLine Reference	14751923:1028
Journal	Blood
Journal Reference	v103 i9 p3448 (2004)
Journal Link	http://www.bloodjournal.org/cgi/content/full/103/9/3448
Organism	Mus musculus
Tissue	endothelial
Source	Curated
CellType	neutrophil


MedLine Reference	10579998:1099
Journal	Genes & Dev
Journal Reference	v13 i22 p2905 (1999)
Journal Link	http://www.genesdev.org/cgi/content/full/13/22/2905
Organism	mouse
Source	Curated


MedLine Reference	10364160:1035
Journal	Genes & Dev
Journal Reference	v13 i11 p1438 (1999)
Journal Link	http://www.genesdev.org/cgi/content/full/13/11/1438
Organism	C-elegans
Source	Curated


MedLine Reference	11054117:1033
Journal	Eur. J. Biochem
Journal Reference	v267 i22 p6642.html) (2000)
Journal Link	http://www.ejbiochem.org/cgi/content/full/267/22/6642.h
CellLineName	293
Organism	rat
Source	Curated


MedLine Reference	10491192:1035
Journal	Eur. J. Biochem
Journal Reference	v265 i1 p353 (1999)
Journal Link	http://www.ejbiochem.org/cgi/content/full/265/1/353
Organism	mouse
Source	Curated


MedLine Reference	9889195:1189
Journal	EMBO
Journal Reference	v18 i2 p386 (1999)
Journal Link	http://embojournal.npgjournals.com/cgi/content/full/18/2/386
CellLineName	SOS
Organism	bovine
Source	Curated


MedLine Reference	9524119:1193
Journal	EMBO
Journal Reference	v17 i7 p1961 (1998)
Journal Link	http://embojournal.npgjournals.com/cgi/content/full/17/7/1961
Organism	rat
Source	Curated


MedLine Reference	11694634:1051
Journal	Nutrition
Journal Reference	v131 i11 p2988S (2001)
Journal Link	http://www.nutrition.org/cgi/content/full/131/11/2988S
Organism	drosophila
Source	Curated


MedLine Reference	12640111:1307
Journal	Mol. Cell. Biol
Journal Reference	v23 i7 p2251 (2003)
Journal Link	http://mcb.asm.org/cgi/content/full/23/7/2251
CellLineName	NIH 3T3
Organism	mouse
Source	Curated


MedLine Reference	11696562:1037
Journal	J. Cell Biol
Journal Reference	v155 i4 p505 (2001)
Journal Link	http://www.jcb.org/cgi/content/full/155/4/505
Source	Curated


MedLine Reference	12176997:1271
Journal	J. Biol. Chem
Journal Reference	v277 i42 p39858 (2002)
Journal Link	http://www.jbc.org/cgi/content/full/277/42/39858
Organism	drosophila
Source	Curated


MedLine Reference	10713065:1027
Journal	J. Biol. Chem
Journal Reference	v275 i11 p7583 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/11/7583
Source	Curated


MedLine Reference	10480933:1325
Journal	J. Biol. Chem
Journal Reference	v274 i38 p27168 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/38/27168
Organism	mouse
Source	Curated


MedLine Reference	10358075:1021
Journal	J. Biol. Chem
Journal Reference	v274 i24 p17179 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/24/17179
Organism	C-elegans
Source	Curated


MedLine Reference	10085060:1120
Journal	J. Biol. Chem
Journal Reference	v274 i13 p8347 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/13/8347
Source	Curated
CellType	b cell


MedLine Reference	12629035:1080
Journal	Hypertension
Journal Reference	v41 i4 p898 (2003)
Journal Link	http://hyper.ahajournals.org/cgi/content/full/41/4/898
Organism	rat
Tissue	smooth muscle
Source	Curated


MedLine Reference	12869584:1207
Journal	Genes & Dev
Journal Reference	v17 i15 p1841 (2003)
Journal Link	http://www.genesdev.org/cgi/content/full/17/15/1841
Organism	mouse
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253.2 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253.2
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253.1
Source	Curated


Journal	Cell
Journal Reference	v100 i1 p113 (2000)
Journal Link	http://www.cell.com/cgi/content/full/100/1/113
Source	Curated


Journal	Cell
Journal Reference	v100 i1 p113.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/100/1/113.1
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p211 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p211.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211.1
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


CellLineName	PF
Source	Curated


MedLine Reference	15187160:1111
Journal	J. Immunol
Journal Reference	v172 i12 p7761 (2004)
Journal Link	http://www.jimmunol.org/cgi/content/full/172/12/7761
CellLineName	CEM
Source	Curated


MedLine Reference	10092583:1025
Journal	J. Biol. Chem
Journal Reference	v274 i14 p9133 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/14/9133
Organism	Mus musculus
Source	Curated


MedLine Reference	15314020:1105
Journal	Genes & Dev
Journal Reference	v18 i16 p1926 (2004)
Journal Link	http://www.genesdev.org/cgi/content/full/18/16/1926
Source	Curated


MedLine Reference	12950263:1028
Journal	Eur. J. Biochem
Journal Reference	v270 i18 p3795 (2003)
Journal Link	http://www.ejbiochem.org/cgi/content/full/270/18/3795
Source	Curated


MedLine Reference	12960100:1187
Journal	Endocrinology
Journal Reference	v144 i11 p4886 (2003)
Journal Link	http://endo.endojournals.org/cgi/content/full/144/11/4886
Source	Curated
CellType	osteoblast


MedLine Reference	12376318:1310
Journal	Endocrin. Metabol
Journal Reference	v283 i5 pE917 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/283/5/E917
Organism	Rattus norvegicus
Tissue	skeletal muscle
Source	Curated


MedLine Reference	12217898:1037
Journal	Endocrin. Metabol
Journal Reference	v283 i4 pE799 (2002)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/283/4/E799
Tissue	skeletal muscle
Source	Curated


MedLine Reference	10698680:3
Source	Curated


MedLine Reference	9637919:1
Source	Curated


MedLine Reference	9512493:1
Organism	rat
Source	Curated


MedLine Reference	10995762:1228
Journal	J. Biol. Chem
Journal Reference	v275 i52 p41201 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/52/41201
Organism	mouse
Source	Curated


MedLine Reference	10945988:1025
Journal	J. Biol. Chem
Journal Reference	v275 i44 p34592 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/44/34592
Organism	rat
Source	Curated


MedLine Reference	10896679:1324
Journal	J. Biol. Chem
Journal Reference	v275 i44 p34424 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/44/34424
Tissue	muscle
Source	Curated


MedLine Reference	10788447:1270
Journal	J. Biol. Chem
Journal Reference	v275 i18 p13377 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/18/13377
CellLineName	COS
Organism	rat
Source	Curated


MedLine Reference	10764742:1245
Journal	J. Biol. Chem
Journal Reference	v275 i27 p20806 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/27/20806
CellLineName	293
Organism	mouse
Source	Curated


MedLine Reference	10753910:1111
Journal	J. Biol. Chem
Journal Reference	v275 i15 p11064 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/15/11064
Organism	mouse
Source	Curated


MedLine Reference	10636870:1310
Journal	J. Biol. Chem
Journal Reference	v275 i3 p1739 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/3/1739
Organism	mouse
Source	Curated


MedLine Reference	10601311:1181
Journal	J. Biol. Chem
Journal Reference	v274 i52 p37400 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/52/37400
Source	Curated


MedLine Reference	10521487:1021
Journal	J. Biol. Chem
Journal Reference	v274 i43 p30927 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/43/30927
Organism	bovine
Organ	heart
Source	Curated


MedLine Reference	10075713:1020
Journal	J. Biol. Chem
Journal Reference	v274 i12 p8117 (1999)
Journal Link	http://www.jbc.org/cgi/content/full/274/12/8117
Organism	mouse
Source	Curated


MedLine Reference	10516192:1257
Journal	Heart Circul
Journal Reference	v277 i4 pH1532 (1999)
Journal Link	http://ajpheart.physiology.org/cgi/content/full/277/4/H1532
Organism	rat
Source	Curated


MedLine Reference	10809663:1257
Journal	Genes & Dev
Journal Reference	v14 i9 p1027 (2000)
Journal Link	http://www.genesdev.org/cgi/content/full/14/9/1027
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253.2 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253.2
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p253.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/253.1
Source	Curated


Journal	Cell
Journal Reference	v100 i1 p113 (2000)
Journal Link	http://www.cell.com/cgi/content/full/100/1/113
Source	Curated


Journal	Cell
Journal Reference	v100 i1 p113.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/100/1/113.1
Source	Curated


Journal	Renal Phys
Journal Reference	v280 i2 pF303 (2001)
Journal Link	http://ajprenal.physiology.org/cgi/content/full/280/2/F303
Organ	kidney
Source	Curated
CellType	fibroblast


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


Journal	Renal Phys
Journal Reference	v280 i2 pF303 (2001)
Journal Link	http://ajprenal.physiology.org/cgi/content/full/280/2/F303
Organ	kidney
Source	Curated
CellType	fibroblast


Journal	Cell
Journal Reference	v103 i2 p211 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p211.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211.1
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


Journal	Renal Phys
Journal Reference	v280 i2 pF303 (2001)
Journal Link	http://ajprenal.physiology.org/cgi/content/full/280/2/F303
Organ	kidney
Source	Curated
CellType	fibroblast


MedLine Reference	10373549:1030
Journal	Mol. Cell. Biol
Journal Reference	v19 i7 p4989 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/7/4989
Source	Curated


MedLine Reference	11052948:1206
Journal	Endocrin. Metabol
Journal Reference	v279 i5 pE947 (2000)
Journal Link	http://ajpendo.physiology.org/cgi/content/full/279/5/E947
Organism	Rattus norvegicus
Tissue	muscle
Source	Curated


MedLine Reference	12970179:1030
Journal	EMBO
Journal Reference	v22 i18 p4666 (2003)
Journal Link	http://embojournal.npgjournals.com/cgi/content/full/22/18/4666
Organism	Mus musculus
Source	Curated
CellType	neural


MedLine Reference	11909969:1032
Journal	Mol. Cell. Biol
Journal Reference	v22 i8 p2799 (2002)
Journal Link	http://mcb.asm.org/cgi/content/full/22/8/2799
Organism	mouse
Source	Curated


MedLine Reference	11839816:1285
Journal	Mol. Cell. Biol
Journal Reference	v22 i5 p1513 (2002)
Journal Link	http://mcb.asm.org/cgi/content/full/22/5/1513
Organism	mouse
Source	Curated


MedLine Reference	10958689:1028
Journal	Mol. Cell. Biol
Journal Reference	v20 i18 p6945 (2000)
Journal Link	http://mcb.asm.org/cgi/content/full/20/18/6945
Organism	drosophila
Source	Curated
CellType	b cell


MedLine Reference	10891507:1357
Journal	Mol. Cell. Biol
Journal Reference	v20 i15 p5712 (2000)
Journal Link	http://mcb.asm.org/cgi/content/full/20/15/5712
Source	Curated


MedLine Reference	10567559:1320
Journal	Mol. Cell. Biol
Journal Reference	v19 i12 p8344 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/12/8344
Organism	yeast
Source	Curated


MedLine Reference	10373554:1205
Journal	Mol. Cell. Biol
Journal Reference	v19 i7 p5061 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/7/5061
Source	Curated


MedLine Reference	10373548:1030
Journal	Mol. Cell. Biol
Journal Reference	v19 i7 p4989 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/7/4989
Source	Curated


MedLine Reference	12700283:1220
Journal	Mol. Cancer Ther
Journal Reference	v2 i4 p389 (2003)
Journal Link	http://mct.aacrjournals.org/cgi/content/full/2/4/389
CellLineName	NIH 3T3
Organism	mouse
Source	Curated


MedLine Reference	14595115:1206
Journal	Mol. Biol. Cell
Journal Reference	v15 i2 p497 (2004)
Journal Link	http://www.molbiolcell.org/cgi/content/full/15/2/497
Organism	mouse
Tissue	muscle
Source	Curated
CellType	myoblast


MedLine Reference	15737995:2
Tissue	endothelial
Source	Curated


MedLine Reference	15743829:1
Organism	mouse
Source	Curated


MedLine Reference	15210700:6
Source	Curated


MedLine Reference	12822887:1
Source	Curated


MedLine Reference	12176338:4
Source	Curated


MedLine Reference	10371193:4
Organism	plant
Source	Curated


MedLine Reference	9895304:2
Organism	mouse
Source	Curated


CellLineName	PF
Source	Curated


CellLineName	PF
Source	Curated


CellLineName	PF
Source	Curated


CellLineName	PF
Source	Curated


CellLineName	PF
Source	Curated


CellLineName	PF
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p185 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/185
Source	Curated


Journal	Renal Phys
Journal Reference	v280 i2 pF303 (2001)
Journal Link	http://ajprenal.physiology.org/cgi/content/full/280/2/F303
Organ	kidney
Source	Curated
CellType	fibroblast


Journal	Cell
Journal Reference	v103 i2 p211 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211
Source	Curated


Journal	Cell
Journal Reference	v103 i2 p211.1 (2000)
Journal Link	http://www.cell.com/cgi/content/full/103/2/211.1
Source	Curated


MedLine Reference	14623982:1027
Journal	PNAS
Journal Reference	v100 i24 p14006 (1996)
Journal Link	http://www.pnas.org/cgi/content/full/100/24/14006
Organism	mouse
Source	Curated


MedLine Reference	11438723:1156
Journal	PNAS
Journal Reference	v98 i14 p7678 (2001)
Journal Link	http://www.pnas.org/cgi/content/full/98/14/7678
Source	Curated


MedLine Reference	10995457:1237
Journal	PNAS
Journal Reference	v97 i20 p10832 (2000)
Journal Link	http://www.pnas.org/cgi/content/full/97/20/10832
Source	Curated


MedLine Reference	10688912:1191
Journal	PNAS
Journal Reference	v97 i5 p2355 (2000)
Journal Link	http://www.pnas.org/cgi/content/full/97/5/2355
Source	Curated


MedLine Reference	10359809:1027
Journal	PNAS
Journal Reference	v96 i12 p6890 (1999)
Journal Link	http://www.pnas.org/cgi/content/full/96/12/6890
Organism	mouse
Source	Curated
CellType	b cell


MedLine Reference	10727509:1038
Journal	Mol. Pharm
Journal Reference	v57 i4 p652 (2000)
Journal Link	http://molpharm.aspetjournals.org/cgi/content/full/57/4/652
Source	Curated


MedLine Reference	11875118:1025
Journal	Mol. Endocrin
Journal Reference	v16 i3 p580 (2002)
Journal Link	http://mend.endojournals.org/cgi/content/full/16/3/580
Organism	mouse
Tissue	follicle
Source	Curated


MedLine Reference	11376107:1030
Journal	Mol. Endocrin
Journal Reference	v15 i6 p867 (2001)
Journal Link	http://mend.endojournals.org/cgi/content/full/15/6/867
Organism	mouse
Tissue	mammary gland
Source	Curated


MedLine Reference	11818508:1074
Journal	Mol. Endocrin
Journal Reference	v16 i2 p378 (2002)
Journal Link	http://mend.endojournals.org/cgi/content/full/16/2/378
Organism	mouse
Source	Curated


MedLine Reference	11463863:1186
Journal	Mol. Endocrin
Journal Reference	v15 i8 p1411 (2001)
Journal Link	http://mend.endojournals.org/cgi/content/full/15/8/1411
Organism	mouse
Source	Curated


MedLine Reference	11158328:1076
Journal	Mol. Endocrin
Journal Reference	v15 i2 p209 (2001)
Journal Link	http://mend.endojournals.org/cgi/content/full/15/2/209
Source	Curated


MedLine Reference	10523666:1330
Journal	Mol. Cell. Biol
Journal Reference	v19 i11 p7771 (1999)
Journal Link	http://mcb.asm.org/cgi/content/full/19/11/7771
Organism	mouse
Source	Curated
CellType	adipocyte


MedLine Reference	14749367:1168
Journal	Mol. Cell. Biol
Journal Reference	v24 i4 p1493 (2004)
Journal Link	http://mcb.asm.org/cgi/content/full/24/4/1493
CellLineName	HEK293t
Source	Curated
CellType	t cell


MedLine Reference	14585963:1282
Journal	Mol. Cell. Biol
Journal Reference	v23 i22 p8019 (2003)
Journal Link	http://mcb.asm.org/cgi/content/full/23/22/8019
Organism	rat
Source	Curated


MedLine Reference	12446787:1210
Journal	Mol. Cell. Biol
Journal Reference	v22 i24 p8695 (2002)
Journal Link	http://mcb.asm.org/cgi/content/full/22/24/8695
CellLineName	A 549
Source	Curated


MedLine Reference	12167714:1109
Journal	Mol. Cell. Biol
Journal Reference	v22 i17 p6247 (2002)
Journal Link	http://mcb.asm.org/cgi/content/full/22/17/6247
CellLineName	HEK 293
Organism	mouse
Source	Curated


MedLine Reference	12923190:1027
Journal	J. Biol. Chem
Journal Reference	v278 i44 p42913 (2003)
Journal Link	http://www.jbc.org/cgi/content/full/278/44/42913
Organism	mouse
Source	Curated


MedLine Reference	12783867:1207
Journal	J. Biol. Chem
Journal Reference	v278 i41 p39311 (2003)
Journal Link	http://www.jbc.org/cgi/content/full/278/41/39311
CellLineName	3T3 L1
Organism	mouse
Source	Curated
CellType	adipocyte


MedLine Reference	12048182:1029
Journal	J. Biol. Chem
Journal Reference	v277 i34 p31099 (2002)
Journal Link	http://www.jbc.org/cgi/content/full/277/34/31099
Source	Curated


MedLine Reference	11278638:1289
Journal	J. Biol. Chem
Journal Reference	v276 i22 p19664 (2001)
Journal Link	http://www.jbc.org/cgi/content/full/276/22/19664
Organism	mouse
Source	Curated


MedLine Reference	10777620:1031
Journal	J. Biol. Chem
Journal Reference	v275 i17 p13142 (2000)
Journal Link	http://www.jbc.org/cgi/content/full/275/17/13142
CellLineName	CML
Organism	mouse
Source	Curated