Cellecta Partners with Ariadne to Provide siRNA Pathway Analysis Services
Cellecta has partnered with Ariadne to offer pathway analysis services for high-throughput siRNA library functional analysis data. The computational validation of positive siRNA clones aims to find plausible signaling mechanisms connecting the effect of inhibition of siRNA target protein and observed phenotype.
Cellecta will use searches against the Ariadne ResNet Mammalian database of pathways and protein interactions to report:
- The lists of pathways affected by each of the identified siRNA clones.
- The common pathways, downstream events or upstream regulators for the sets of siRNAs.
- Expression profiles for corresponding genes as available from the public datasets.
- Similar biological effects of siRNA targets or other functionally related genes if known in the literature.
As an option, the analysis results can be delivered in a format compatible with Pathway Studio to enable additional analysis of pathways involved and integration with the prior knowledge and profiling data.
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Press Contact:
Natalia Alexandrova
Ariadne Genomics
natal@ariadnegenomics.com
Tel: (240) 453-6296 x111
www.ariadnegenomics.com
